Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | truncNotch |
| GeneSet | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS |
| Enrichment Score (ES) | 0.8327041 |
| Normalized Enrichment Score (NES) | 1.6834164 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.042691834 |
| FWER p-Value | 0.045 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SDHC | 3140347 6100156 | 5 | 5.850 | 0.1520 | Yes | ||
| 2 | PGK1 | 1570494 630300 | 11 | 5.024 | 0.2825 | Yes | ||
| 3 | TPI1 | 1500215 2100154 | 25 | 4.295 | 0.3936 | Yes | ||
| 4 | PFKM | 1990156 5720168 | 34 | 3.868 | 0.4938 | Yes | ||
| 5 | PKM2 | 6520403 70500 | 160 | 2.217 | 0.5448 | Yes | ||
| 6 | ENO1 | 5340128 | 161 | 2.215 | 0.6025 | Yes | ||
| 7 | ENO3 | 5270136 | 198 | 2.033 | 0.6534 | Yes | ||
| 8 | FBP1 | 1470762 | 240 | 1.886 | 0.7003 | Yes | ||
| 9 | ALDOA | 6290672 | 242 | 1.875 | 0.7490 | Yes | ||
| 10 | PGAM2 | 3610605 | 264 | 1.791 | 0.7945 | Yes | ||
| 11 | SDHB | 3120398 4780113 3710435 | 615 | 1.174 | 0.8062 | Yes | ||
| 12 | PFKL | 6200167 | 661 | 1.110 | 0.8327 | Yes | ||
| 13 | MDH2 | 1850601 | 1242 | 0.693 | 0.8195 | No | ||
| 14 | PGAM1 | 2570133 | 1480 | 0.571 | 0.8216 | No | ||
| 15 | SDHD | 2570128 | 1985 | 0.399 | 0.8049 | No | ||
| 16 | ACO1 | 50114 | 2245 | 0.332 | 0.7996 | No | ||
| 17 | DLST | 2320722 | 2595 | 0.241 | 0.7871 | No | ||
| 18 | CS | 5080600 | 2925 | 0.176 | 0.7739 | No | ||
| 19 | ACO2 | 4230600 | 3033 | 0.162 | 0.7724 | No | ||
| 20 | IDH2 | 2680397 | 4049 | 0.074 | 0.7197 | No | ||
| 21 | GAPDHS | 2690463 | 4537 | 0.054 | 0.6949 | No | ||
| 22 | FBP2 | 1580193 | 5674 | 0.029 | 0.6345 | No | ||
| 23 | AMAC1 | 940270 | 6082 | 0.023 | 0.6131 | No | ||
| 24 | DLD | 4150403 6590341 | 6307 | 0.020 | 0.6016 | No | ||
| 25 | PDHX | 870315 | 7651 | 0.011 | 0.5296 | No | ||
| 26 | PKLR | 1170400 2470114 | 9933 | 0.003 | 0.4069 | No | ||
| 27 | ALDOB | 4730324 | 11700 | -0.002 | 0.3119 | No | ||
| 28 | SDHA | 7000056 | 12361 | -0.005 | 0.2765 | No | ||
| 29 | MDH1 | 6660358 6760731 | 12968 | -0.008 | 0.2441 | No | ||
| 30 | PGK2 | 2650091 | 13736 | -0.015 | 0.2032 | No | ||
| 31 | ALDOC | 450121 610427 | 13898 | -0.017 | 0.1950 | No | ||
| 32 | OGDH | 3840333 6350100 | 14787 | -0.045 | 0.1484 | No | ||
| 33 | SUCLA2 | 730632 1170292 | 14933 | -0.054 | 0.1419 | No | ||
| 34 | BPGM | 5080520 | 15363 | -0.087 | 0.1211 | No | ||
| 35 | PDHB | 70215 610086 | 15693 | -0.121 | 0.1066 | No | ||
| 36 | DLAT | 430452 | 16052 | -0.170 | 0.0917 | No | ||
| 37 | ENO2 | 2320068 | 16609 | -0.296 | 0.0695 | No | ||
| 38 | PFKP | 70138 6760040 1170278 | 17534 | -0.650 | 0.0367 | No | ||
| 39 | IDH1 | 1990021 | 17822 | -0.827 | 0.0427 | No |
